Proton Beam Therapy for Local Recurrence of Rectal Cancer

Background/Aim: Curing local recurrence of rectal cancer (LRRC) is difficult with conventional photon radiotherapy. Proton beam therapy (PBT) on the other hand, has unique physical characteristics that permit higher doses to LRRC while minimizing side effects surrounding organs. However, efficacy PBT controlling not yet been reported. This study aimed evaluate clinical outcomes and toxicities for LRRC. Patients Methods: Clinical were retrospectively evaluated 12 patients 13 total lesions had received at our institute. Results: The median follow-up period from initiation was 42.9 months. 3-year control, progression-free survival overall rates 80.2%, 12.1% 71.3%, respectively. Median time 67.1 There no severe acute or late adverse events. Conclusion: could be a safe effective treatment method